The AD8422ARMZ-R7 is a low-cost, high-performance instrumentation amplifier from Analog Devices in MSOP-8, with gain set by a single external resistor (RG): Gain = 1 + (19.8k / RG). Gains from 1 to 1000 are achievable: G=1 (RG open), G=10 (RG=2.2k), G=100 (RG=200), G=1000 (RG=19.8 ohm). The three-op-amp architecture provides: (1) Two input buffers (preamps) that present high impedance to the signal source and amplify the differential signal; (2) A difference amplifier that rejects the common-mode voltage and provides the single-ended output. The input offset voltage is 25uV typical (150uV max over temperature), and the input bias current is 200pA. The CMRR (common-mode rejection ratio) is 80dB at G=1 and 120dB at G>=100, critical for rejecting noise in bridge and current-sense applications. The bandwidth is 10MHz at G=1 and 2MHz at G=10, decreasing to 20kHz at G=1000. The supply current is 330uA per amplifier, and the supply voltage range is +/-2.5V to +/-18V (or 5V to 36V single-supply). The REF pin allows output level shifting: connecting REF to a DAC output enables bidirectional current measurement. The output can swing to within 1.2V of the supply rails. The AD8422 is the cost-optimized successor to the AD8221, offering similar performance at lower cost. The -ARMZ-R7 suffix specifies MSOP-8, tape-and-reel. Applications include bridge transducer amplification, medical ECG/EEG, and industrial current sensing.