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ADS1299IPAG

8-channel 24-bit EEG AFE, low noise, TQFP-64

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Manufacturer Part：

ADS1299IPAG

Package：

TQFP-64 (10.0 x 10.0 x 1.20 mm)

Brand：

Product Categories：

Analog Linear ICs, Integrated Circuits ICs

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Description

ADS1299IPAG Overview

The ADS1299IPAG is an 8-channel 24-bit EEG front-end ADC from Texas Instruments with integrated PGA (gain 1-24), only 70nV/sqrt(Hz) input noise, SPI interface, in a TQFP-64 package, specifically designed for EEG and biopotential signal measurement.

Key Features

Resolution: 24-bit
8 simultaneous sampling channels
PGA gain: 1-24
Input noise: 70nV/sqrt(Hz)
SPI interface
Data rate: 250-16k SPS
Built-in right-leg drive amplifier

Product Introduction:ADS1299IPAG Product Introduction

The ADS1299IPAG is an 8-channel, 24-bit simultaneous-sampling delta-sigma analog front-end (AFE) from Texas Instruments designed for biopotential measurements, housed in a 64-pin TQFP (10 x 10 mm) package. It integrates 8 low-noise programmable gain amplifiers (PGA) with gain settings of 1 to 24, achieving 1.0 uVpp input-referred noise at 70 Hz bandwidth with gain of 24. The device features -110 dB CMRR, 300 pA input bias current, data rates from 250 SPS to 16 kSPS, and an integrated bias drive amplifier, lead-off detection, test signal generation, oscillator, and voltage reference. Operating from a 5 V analog and 1.8 V to 3.6 V digital supply, it dissipates only 5 mW per channel.

Working Principle:ADS1299IPAG Working Principle

The ADS1299IPAG converts analog biopotential signals to digital data using 8 independent delta-sigma modulator channels followed by shared digital decimation filters. Each channel has a flexible input multiplexer that can connect to external electrode inputs, internal test signals, temperature sensor, or shorted inputs for calibration and noise measurement. The PGA amplifies the differential input signal by the programmed gain factor (1, 2, 4, 6, 8, 12, or 24) before the modulator. Each delta-sigma modulator oversamples at a high rate (fCLK/4), producing a 1-bit stream whose density represents the input amplitude. The digital decimation filter processes this bitstream to produce 24-bit output words at the selected data rate (250 SPS to 16 kSPS). The bias drive amplifier generates a common-mode reference voltage that is fed back to the patient through a bias electrode, actively canceling common-mode interference. Lead-off detection uses either DC current excitation or AC current excitation (using internal current sources and sinks) to monitor electrode connectivity. The SPI-compatible serial interface reads conversion results and writes configuration registers, supporting daisy-chain connection of multiple ADS1299 devices for high-channel-count EEG systems.

Pin Description:ADS1299IPAG Pin Definition and Functions

Pin Group	Count	Description
AIN1P/N – AIN8P/N	16	8 differential analog input pairs for electrode connections
AVDD, AVSS	4	Analog power supply (4.75-5.25 V) and ground
DVDD, DGND	4	Digital power supply (1.8-3.6 V) and ground
SCLK, DIN, DOUT, CS	4	SPI interface pins for serial communication
DRDY	1	Data ready output; falls when new conversion data is available
START	1	Start/stop conversions; active high
RESET	1	Reset input; active low, resets all registers to default
CLKSEL, CLK	2	Clock source selection and external clock input
REFINP/N, REFP/N	4	Reference input and output pins (internal or external reference)
BIASIN, BIASREF, BIASOUT	3	Bias drive amplifier input, reference, and output
GPIO0-GPIO3	4	General-purpose I/O pins
DAISY_IN	1	Daisy-chain data input for cascading multiple devices

Application Scenarios:In which products and applications isADS1299IPAG used

EEG Systems: Clinical and research electroencephalography with 8-64 channels using daisy-chained devices
ECG/EKG Recording: Multi-lead electrocardiogram acquisition with high CMRR for diagnostic quality
Evoked Potentials: Auditory and somatosensory evoked potential recording in neurology labs
Sleep Study Monitors: Polysomnography systems combining EEG, EMG, and EOG channels
BIS Monitoring: Bispectral index monitoring for anesthesia depth assessment in operating rooms

Alternative Models:What chips are recommended as replacements for ADS1299IPAG

Model	Manufacturer	Channels	Resolution	Noise	Package
ADS1299-4IPAG	Texas Instruments	4	24-bit	1 uVpp	TQFP-64
ADS1299-6IPAG	Texas Instruments	6	24-bit	1 uVpp	TQFP-64
ADS1298IPAG	Texas Instruments	8	24-bit	4 uVpp	TQFP-64
ADS1294IPAG	Texas Instruments	4	24-bit	1 uVpp	TQFP-64
RHD2216	Intan Technologies	16	16-bit	2.4 uVrms	QFN-56

ADS1299IPAG is an 8-channel 24-bit biopotential AFE from TI in TQFP-64 with 1µVPP noise. The ADS1299-4IPAG provides 4 channels in the same package for lower-cost EEG applications. ADS1298IPAG adds pace detection for ECG. For single-channel, ADS1291 offers 24-bit with 2 channels in TQFP-32. The ADS1256 from TI is an alternative 24-bit ADC with 8 channels and 23kSPS rate for general-purpose precision measurement.